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The Dose Inside Vital Beautie's New PDRN Drink Tells a Story

Vital Beautie's new after-procedure drink pairs a tenth of a gram of PDRN, an ingredient whose track record is in injectable skin boosters, with six grams of collagen, an ingredient Korea's food regulator already recognizes at far lower oral doses.

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Vital Beautie, Amorepacific's ingestible beauty line, is launching Super Collagen PDRN, a two-part drink built for what the brand calls an eating after-routine: something to take once a day, at home, following an in-clinic procedure. Each dose pairs a tablet holding 100 milligrams of PDRN sourced from Alaska salmon with a liquid ampoule carrying 6,000 milligrams of low-molecular collagen, along with hyaluronic acid and glutathione. The brand says dermatologists were involved in development.

Where PDRN's evidence actually lives

PDRN, short for polydeoxyribonucleotide, built its reputation in Korean dermatology as an injectable ingredient: the salmon-DNA skin booster shots used in clinics to calm and rebuild tissue right where a needle has just done damage, by activating adenosine receptors near the injury site and prompting fibroblasts to make more collagen. That is a local, site-specific action. Swallowing PDRN is a different delivery problem, and the current wave of oral launches, including recent entries from CJ Wellcare and HLB Pharmaceutical, has so far cited the ingredient's injectable pedigree without pointing to oral trials of their own.

A tell inside the dose

Collagen peptide, by contrast, already holds recognized status in Korea's health functional food system, with a government-set intake band of 1 to 3 grams a day for skin-moisture claims. Vital Beautie's drink carries 6 grams of it, above that range, while PDRN sits at a tenth of a gram. The newer ingredient gets the product's name; the older, better-documented one carries the dose.

Sources: Ministry of Food and Drug Safety, functional food ingredient database